BDBM50143710 8-(2-{[2-(2,5-Dichloro-phenylamino)-ethyl]-methyl-amino}-ethyl)-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL55460

SMILES CN(CCNc1cc(Cl)ccc1Cl)CCN1C(=O)CC2(CCCC2)CC1=O

InChI Key InChIKey=CAFBNEJZNQABOY-UHFFFAOYSA-N

Data  2 KI

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143710   

TargetAlpha-1D adrenergic receptor(Rattus norvegicus (Rat))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50143710(8-(2-{[2-(2,5-Dichloro-phenylamino)-ethyl]-methyl-...)
Show SMILES CN(CCNc1cc(Cl)ccc1Cl)CCN1C(=O)CC2(CCCC2)CC1=O
Show InChI InChI=1S/C20H27Cl2N3O2/c1-24(9-8-23-17-12-15(21)4-5-16(17)22)10-11-25-18(26)13-20(14-19(25)27)6-2-3-7-20/h4-5,12,23H,2-3,6-11,13-14H2,1H3
Affinity DataKi:  674nMAssay Description:Binding affinity to the adrenergic receptor alpha-1D of rat aortaMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50143710(8-(2-{[2-(2,5-Dichloro-phenylamino)-ethyl]-methyl-...)
Show SMILES CN(CCNc1cc(Cl)ccc1Cl)CCN1C(=O)CC2(CCCC2)CC1=O
Show InChI InChI=1S/C20H27Cl2N3O2/c1-24(9-8-23-17-12-15(21)4-5-16(17)22)10-11-25-18(26)13-20(14-19(25)27)6-2-3-7-20/h4-5,12,23H,2-3,6-11,13-14H2,1H3
Affinity DataKi:  717nMAssay Description:Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioli...More data for this Ligand-Target Pair