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BDBM50145265 CHEMBL81000::N-{4-[4-(4-Fluoro-phenyl)-thiazol-2-ylamino]-cyclohexylmethyl}-methanesulfonamide

SMILES: CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(cs1)-c1ccc(F)cc1

InChI Key: InChIKey=AUBOGZYAGLUUGF-NNUKFRKNSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145265   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))
BDBM50145265
PNG
(CHEMBL81000 | N-{4-[4-(4-Fluoro-phenyl)-thiazol-2-...)
Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(cs1)-c1ccc(F)cc1
Show InChI InChI=1S/C17H22FN3O2S2/c1-25(22,23)19-10-12-2-8-15(9-3-12)20-17-21-16(11-24-17)13-4-6-14(18)7-5-13/h4-7,11-12,15,19H,2-3,8-10H2,1H3,(H,20,21)/t12-,15-
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 23n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound against human neuropeptide Y5 receptor


Bioorg Med Chem Lett 14: 2451-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.014
BindingDB Entry DOI: 10.7270/Q2WM1CV1
More data for this
Ligand-Target Pair