BDBM50145645 CHEMBL3763343

SMILES Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1cc(nc(N)n1)-c1ccc(NS(C)(=O)=O)cc1)C(F)(F)F

InChI Key InChIKey=PUPOESSMOIKNFU-OAQYLSRUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145645   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145645(CHEMBL3763343)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed