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BDBM50145674 CHEMBL2436531

SMILES: CCOC(=O)c1sc(N\N=C\c2ccc(O)c(OC)c2)nc1C

InChI Key: InChIKey=VZZHFEFHMHCYCG-LZYBPNLTSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145674   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucyl-tRNA synthetase


(Homo sapiens (Human))
BDBM50145674
PNG
(CHEMBL2436531)
Show SMILES CCOC(=O)c1sc(N\N=C\c2ccc(O)c(OC)c2)nc1C
Show InChI InChI=1S/C15H17N3O4S/c1-4-22-14(20)13-9(2)17-15(23-13)18-16-8-10-5-6-11(19)12(7-10)21-3/h5-8,19H,4H2,1-3H3,(H,17,18)/b16-8+
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MMDB

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Article
PubMed
n/an/a 1.16E+5n/an/an/an/an/an/a



NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...


Bioorg Med Chem 24: 1023-31 (2016)


Article DOI: 10.1016/j.bmc.2016.01.028
BindingDB Entry DOI: 10.7270/Q2RN39Q8
More data for this
Ligand-Target Pair