BDBM50146475 CHEMBL98202::N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(tetrahydro-thiopyran-4-ylidenemethyl)-ethyl]-formamide

SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2\[#6]-[#6]-[#16]-[#6]-[#6]-2)-[#7](-[#8])-[#6]=O)c2ccccc2n1

InChI Key InChIKey=KQXZHGMAVQYCLA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50146475   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146475(CHEMBL98202 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146475(CHEMBL98202 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146475(CHEMBL98202 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146475(CHEMBL98202 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146475(CHEMBL98202 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146475(CHEMBL98202 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed