BDBM50146588 CHEMBL3764145
SMILES Fc1ccc(NC(=O)Nc2cccc(c2)-c2cnc3c(NC(=O)c4cc(Cl)cc(Cl)c4)nccn23)c(F)c1
InChI Key InChIKey=JTLWTLJMIQDBQM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50146588
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: >1.25E+4nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: >1.25E+4nMAssay Description:Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...More data for this Ligand-Target Pair