BDBM50146588 CHEMBL3764145

SMILES Fc1ccc(NC(=O)Nc2cccc(c2)-c2cnc3c(NC(=O)c4cc(Cl)cc(Cl)c4)nccn23)c(F)c1

InChI Key InChIKey=JTLWTLJMIQDBQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146588   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146588(CHEMBL3764145)
Affinity DataIC50: >1.25E+4nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146588(CHEMBL3764145)
Affinity DataIC50: >1.25E+4nMAssay Description:Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed