BDBM50146770 CHEMBL94646::N-(1-{1-[1-Hydroxy-2-(3-phenyl-propylcarbamoyl)-ethyl]-3-methyl-butylcarbamoyl}-2-methyl-butyl)-4-methylaminomethyl-benzamide::PS-222036

SMILES CCC(C)C(NC(=O)c1ccc(CNC)cc1)C(=O)NC(CC(C)C)C(O)CC(=O)NCCCc1ccccc1

InChI Key InChIKey=POMPAVNXKGHLHK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146770   

TargetPlasmepsin II(Plasmodium falciparum)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50146770(CHEMBL94646 | N-(1-{1-[1-Hydroxy-2-(3-phenyl-propy...)
Affinity DataKi:  440nMAssay Description:In vitro inhibition of plasmepsin-2 from Plasmodium falciparum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50146770(CHEMBL94646 | N-(1-{1-[1-Hydroxy-2-(3-phenyl-propy...)
Affinity DataKi:  440nMAssay Description:Binding affinity towards plasmepsin-2 in Plasmodium falciparum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Universitat Pompeu Fabra

Curated by ChEMBL
LigandPNGBDBM50146770(CHEMBL94646 | N-(1-{1-[1-Hydroxy-2-(3-phenyl-propy...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity towards human cathepsin D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Universitat Pompeu Fabra

Curated by ChEMBL
LigandPNGBDBM50146770(CHEMBL94646 | N-(1-{1-[1-Hydroxy-2-(3-phenyl-propy...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibitory activity against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed