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BDBM50147184 3-{[1-(2-Amino-acetylamino)-3-phenyl-propyl]-hydroxy-phosphinoyl}-propionic acid methyl ester; hydrochloride::CHEMBL541315

SMILES: COC(=O)CCP(O)(=O)C(CCc1ccccc1)NC(=O)CN

InChI Key: InChIKey=GWLXKYUBSSNZRI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147184   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase I


(Mus musculus)
BDBM50147184
PNG
(3-{[1-(2-Amino-acetylamino)-3-phenyl-propyl]-hydro...)
Show SMILES COC(=O)CCP(O)(=O)C(CCc1ccccc1)NC(=O)CN
Show InChI InChI=1S/C15H23N2O5P/c1-22-15(19)9-10-23(20,21)14(17-13(18)11-16)8-7-12-5-3-2-4-6-12/h2-6,14H,7-11,16H2,1H3,(H,17,18)(H,20,21)
PDB
MMDB

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PC sid
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Similars

Article
PubMed
3.12E+5n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay


Bioorg Med Chem Lett 14: 3113-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.028
BindingDB Entry DOI: 10.7270/Q26Q1XT1
More data for this
Ligand-Target Pair