BDBM50147818 (2-[6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-YL)ETHYL]AMINO}-2-OXOPYRAZIN-1(2H)-YL]-N-[5-CHLORO-2-(1H-TETRAZOL-1-YL)BENZYL]ACETAMIDE::2-{6-Chloro-3-[2,2-difluoro-2-(1-oxy-pyridin-2-yl)-ethylamino]-2-oxo-2H-pyrazin-1-yl}-N-(5-chloro-2-tetrazol-1-yl-benzyl)-acetamide::CHEMBL103461

SMILES [O-][n+]1ccccc1C(F)(F)CNc1ncc(Cl)n(CC(=O)NCc2cc(Cl)ccc2-n2cnnn2)c1=O

InChI Key InChIKey=QOKFRQVFMZFNBC-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50147818   

TargetProthrombin(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50147818((2-[6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-...)
Affinity DataKi:  0.00100nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50147818((2-[6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-...)
Affinity DataKi:  0.00140nMAssay Description:Binding affinity to thrombin (unknown origin)More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50147818((2-[6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-...)
Affinity DataKi:  0.00140nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50147818((2-[6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-...)
Affinity DataKi:  0.00140nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair