BDBM50149555 CHEMBL3770278

SMILES CC(C)Oc1ccc(cc1Cl)-c1nnc(s1)-n1nc(C)c(CC(O)=O)c1C

InChI Key InChIKey=AJIKYUOKNHOLKA-UHFFFAOYSA-N

Data  3 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149555   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50149555(CHEMBL3770278)
Show SMILES CC(C)Oc1ccc(cc1Cl)-c1nnc(s1)-n1nc(C)c(CC(O)=O)c1C
Show InChI InChI=1S/C18H19ClN4O3S/c1-9(2)26-15-6-5-12(7-14(15)19)17-20-21-18(27-17)23-11(4)13(8-16(24)25)10(3)22-23/h5-7,9H,8H2,1-4H3,(H,24,25)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO-K1 EDG1 cells by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50149555(CHEMBL3770278)
Show SMILES CC(C)Oc1ccc(cc1Cl)-c1nnc(s1)-n1nc(C)c(CC(O)=O)c1C
Show InChI InChI=1S/C18H19ClN4O3S/c1-9(2)26-15-6-5-12(7-14(15)19)17-20-21-18(27-17)23-11(4)13(8-16(24)25)10(3)22-23/h5-7,9H,8H2,1-4H3,(H,24,25)
Affinity DataEC50: <3.16E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in RBL cells by [35S]GTP-gammaS accumulation assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50149555(CHEMBL3770278)
Show SMILES CC(C)Oc1ccc(cc1Cl)-c1nnc(s1)-n1nc(C)c(CC(O)=O)c1C
Show InChI InChI=1S/C18H19ClN4O3S/c1-9(2)26-15-6-5-12(7-14(15)19)17-20-21-18(27-17)23-11(4)13(8-16(24)25)10(3)22-23/h5-7,9H,8H2,1-4H3,(H,24,25)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in RH7777 cells by [35S]GTP-gammaS accumulation assayMore data for this Ligand-Target Pair