BDBM501497 5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl]-N-[(2-methyltetrazol-5- yl)methyl]pyrazolo[4,3-b]pyridin-7-amine, enantiomer 2::US11026923, Example 127

SMILES CCOc1ncccc1-c1cc(NCc2nnn(C)n2)c(NC(C)CC)c(n1)C(C)=N

InChI Key InChIKey=KPXIVBJCVBNAQF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 501497   

LigandPNGBDBM501497(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...)
Affinity DataIC50:  1.80nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM501497(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...)
Affinity DataIC50:  5.10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM501497(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...)
Affinity DataIC50:  0.310nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent