BDBM50149709 5-Iodo-thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL362101

SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(I)s3)CC2)c1Cl

InChI Key InChIKey=CPTTYKNXUVQTGN-UHFFFAOYSA-N

Data  6 KI

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50149709   

TargetD(3) dopamine receptor(Homo sapiens (Human))
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50149709(5-Iodo-thiophene-2-carboxylic acid {4-[4-(2,3-dich...)
Show SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(I)s3)CC2)c1Cl
Show InChI InChI=1S/C19H22Cl2IN3OS/c20-14-4-3-5-15(18(14)21)25-12-10-24(11-13-25)9-2-1-8-23-19(26)16-6-7-17(22)27-16/h3-7H,1-2,8-13H2,(H,23,26)
Affinity DataKi:  1.40nMAssay Description:Binding affinity towards human D3 receptor using [3H]-spiperone expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50149709(5-Iodo-thiophene-2-carboxylic acid {4-[4-(2,3-dich...)
Show SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(I)s3)CC2)c1Cl
Show InChI InChI=1S/C19H22Cl2IN3OS/c20-14-4-3-5-15(18(14)21)25-12-10-24(11-13-25)9-2-1-8-23-19(26)16-6-7-17(22)27-16/h3-7H,1-2,8-13H2,(H,23,26)
Affinity DataKi:  24nMAssay Description:Binding affinity towards 5-HT1A receptor from porcine cortical membranes using [3H]-8-OH-DPATMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50149709(5-Iodo-thiophene-2-carboxylic acid {4-[4-(2,3-dich...)
Show SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(I)s3)CC2)c1Cl
Show InChI InChI=1S/C19H22Cl2IN3OS/c20-14-4-3-5-15(18(14)21)25-12-10-24(11-13-25)9-2-1-8-23-19(26)16-6-7-17(22)27-16/h3-7H,1-2,8-13H2,(H,23,26)
Affinity DataKi:  32nMAssay Description:Binding affinity towards human D2 short receptor using [3H]-spiperone expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50149709(5-Iodo-thiophene-2-carboxylic acid {4-[4-(2,3-dich...)
Show SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(I)s3)CC2)c1Cl
Show InChI InChI=1S/C19H22Cl2IN3OS/c20-14-4-3-5-15(18(14)21)25-12-10-24(11-13-25)9-2-1-8-23-19(26)16-6-7-17(22)27-16/h3-7H,1-2,8-13H2,(H,23,26)
Affinity DataKi:  89nMAssay Description:Binding affinity towards human D2 long receptor using [3H]-spiperone expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50149709(5-Iodo-thiophene-2-carboxylic acid {4-[4-(2,3-dich...)
Show SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(I)s3)CC2)c1Cl
Show InChI InChI=1S/C19H22Cl2IN3OS/c20-14-4-3-5-15(18(14)21)25-12-10-24(11-13-25)9-2-1-8-23-19(26)16-6-7-17(22)27-16/h3-7H,1-2,8-13H2,(H,23,26)
Affinity DataKi:  130nMAssay Description:Binding affinity towards human D4.4 receptor using [3H]-spiperone expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Sus scrofa)
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50149709(5-Iodo-thiophene-2-carboxylic acid {4-[4-(2,3-dich...)
Show SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(I)s3)CC2)c1Cl
Show InChI InChI=1S/C19H22Cl2IN3OS/c20-14-4-3-5-15(18(14)21)25-12-10-24(11-13-25)9-2-1-8-23-19(26)16-6-7-17(22)27-16/h3-7H,1-2,8-13H2,(H,23,26)
Affinity DataKi:  820nMAssay Description:Binding affinity towards D1 receptor from porcine striatal membranes using [3H]-SCH- 23390More data for this Ligand-Target Pair