BDBM50150673 CHEMBL363466::[(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-dimethyl-amine

SMILES COc1cccc(OC)c1-c1cccc2C[C@H](CCc12)N(C)C

InChI Key InChIKey=BFHVQDBLFZYJPG-HNNXBMFYSA-N

Data  6 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50150673   

Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  2.55nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  2.55nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  241nMAssay Description:Inhibition of [3H]-Raclopride binding to Dopamine receptor D2A in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  241nMAssay Description:Inhibition of [3H]-Raclopride binding to human dopamine D2A receptor expressed in Ltk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to human 5-HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]- GR-65630 binding to rabbit ileum muscularis 5-HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]- GR-113808 binding to guinea pig striatum 5-HT4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed