BDBM50150715 4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amide::4'-fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amide::CHEMBL178707::N-(6-((dimethylamino)methyl)-5,6,7,8-tetrahydronaphthalen-2-yl)-4'-fluorobiphenyl-4-carboxamide::T-226296
SMILES CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccc(F)cc3)ccc2C1
InChI Key InChIKey=GXAQELJVODWLDD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50150715
Affinity DataKi: 5.5nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Chemical Industries
Curated by PDSP Ki Database
Takeda Chemical Industries
Curated by PDSP Ki Database
Affinity DataKi: 38nMAssay Description:Displacement of [125I][Phe13, Tyr19]MCH from human recombinant MCHR1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]-MCH from human MCHR1 expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced GTPgammaS binding after 60 mins by scintillation coun...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Chemical Industries
Curated by PDSP Ki Database
Takeda Chemical Industries
Curated by PDSP Ki Database
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]-MCH(4-19) from human MCHR1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at MCH1R (unknown origin) by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of Melanin-concentrating hormone 1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair