BDBM50152049 3-(2,4-Dichloro-phenyl)-7-dicyclopropylmethyl-8-ethyl-1-methyl-1,2,3,7-tetrahydro-purin-6-one::CHEMBL426607

SMILES CCc1nc2N(CN(C)C(=O)c2n1C(C1CC1)C1CC1)c1ccc(Cl)cc1Cl

InChI Key InChIKey=AUECLXXBKDPVTQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152049   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152049(3-(2,4-Dichloro-phenyl)-7-dicyclopropylmethyl-8-et...)
Affinity DataIC50:  6nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152049(3-(2,4-Dichloro-phenyl)-7-dicyclopropylmethyl-8-et...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [125I]- sauvagine binding to corticotropin releasing factor receptor 2 of porcine choroid plexusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed