BDBM50152506 CHEMBL186735::{2-Methyl-1-[4-(2-phenoxy-ethoxy)-benzoyl]-1H-indol-4-yl}-acetic acid

SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCOc2ccccc2)cc1

InChI Key InChIKey=BCXKWNRNWURDCY-UHFFFAOYSA-N

Data  6 KI  2 IC50

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50152506   

TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152506(CHEMBL186735 | {2-Methyl-1-[4-(2-phenoxy-ethoxy)-b...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCOc2ccccc2)cc1
Show InChI InChI=1S/C26H23NO5/c1-18-16-23-20(17-25(28)29)6-5-9-24(23)27(18)26(30)19-10-12-22(13-11-19)32-15-14-31-21-7-3-2-4-8-21/h2-13,16H,14-15,17H2,1H3,(H,28,29)
Affinity DataKi:  10nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptorMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152506(CHEMBL186735 | {2-Methyl-1-[4-(2-phenoxy-ethoxy)-b...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCOc2ccccc2)cc1
Show InChI InChI=1S/C26H23NO5/c1-18-16-23-20(17-25(28)29)6-5-9-24(23)27(18)26(30)19-10-12-22(13-11-19)32-15-14-31-21-7-3-2-4-8-21/h2-13,16H,14-15,17H2,1H3,(H,28,29)
Affinity DataKi:  290nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152506(CHEMBL186735 | {2-Methyl-1-[4-(2-phenoxy-ethoxy)-b...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCOc2ccccc2)cc1
Show InChI InChI=1S/C26H23NO5/c1-18-16-23-20(17-25(28)29)6-5-9-24(23)27(18)26(30)19-10-12-22(13-11-19)32-15-14-31-21-7-3-2-4-8-21/h2-13,16H,14-15,17H2,1H3,(H,28,29)
Affinity DataKi:  540nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP2More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152506(CHEMBL186735 | {2-Methyl-1-[4-(2-phenoxy-ethoxy)-b...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCOc2ccccc2)cc1
Show InChI InChI=1S/C26H23NO5/c1-18-16-23-20(17-25(28)29)6-5-9-24(23)27(18)26(30)19-10-12-22(13-11-19)32-15-14-31-21-7-3-2-4-8-21/h2-13,16H,14-15,17H2,1H3,(H,28,29)
Affinity DataKi:  5.60E+3nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP1More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152506(CHEMBL186735 | {2-Methyl-1-[4-(2-phenoxy-ethoxy)-b...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCOc2ccccc2)cc1
Show InChI InChI=1S/C26H23NO5/c1-18-16-23-20(17-25(28)29)6-5-9-24(23)27(18)26(30)19-10-12-22(13-11-19)32-15-14-31-21-7-3-2-4-8-21/h2-13,16H,14-15,17H2,1H3,(H,28,29)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP3More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152506(CHEMBL186735 | {2-Methyl-1-[4-(2-phenoxy-ethoxy)-b...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCOc2ccccc2)cc1
Show InChI InChI=1S/C26H23NO5/c1-18-16-23-20(17-25(28)29)6-5-9-24(23)27(18)26(30)19-10-12-22(13-11-19)32-15-14-31-21-7-3-2-4-8-21/h2-13,16H,14-15,17H2,1H3,(H,28,29)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP4More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152506(CHEMBL186735 | {2-Methyl-1-[4-(2-phenoxy-ethoxy)-b...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCOc2ccccc2)cc1
Show InChI InChI=1S/C26H23NO5/c1-18-16-23-20(17-25(28)29)6-5-9-24(23)27(18)26(30)19-10-12-22(13-11-19)32-15-14-31-21-7-3-2-4-8-21/h2-13,16H,14-15,17H2,1H3,(H,28,29)
Affinity DataIC50: 250nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152506(CHEMBL186735 | {2-Methyl-1-[4-(2-phenoxy-ethoxy)-b...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCOc2ccccc2)cc1
Show InChI InChI=1S/C26H23NO5/c1-18-16-23-20(17-25(28)29)6-5-9-24(23)27(18)26(30)19-10-12-22(13-11-19)32-15-14-31-21-7-3-2-4-8-21/h2-13,16H,14-15,17H2,1H3,(H,28,29)
Affinity DataIC50: 50nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing mouse Prostaglandin D2 rece...More data for this Ligand-Target Pair