BDBM50153206 2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-piperidin-1-yl-propyl)-benzamide::CHEMBL182554

SMILES COc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1

InChI Key InChIKey=DCMOVMXTFVOSNS-UHFFFAOYSA-N

Data  4 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153206   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7TM Pharma A/S

Curated by ChEMBL
LigandPNGBDBM50153206(2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-pip...)
Show SMILES COc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1
Show InChI InChI=1S/C29H34N4O4/c1-36-27-21-23(13-16-26(27)28(34)30-17-8-20-33-18-6-3-7-19-33)32-29(35)31-22-11-14-25(15-12-22)37-24-9-4-2-5-10-24/h2,4-5,9-16,21H,3,6-8,17-20H2,1H3,(H,30,34)(H2,31,32,35)
Affinity DataIC50: 50nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligandMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
7TM Pharma A/S

Curated by ChEMBL
LigandPNGBDBM50153206(2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-pip...)
Show SMILES COc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1
Show InChI InChI=1S/C29H34N4O4/c1-36-27-21-23(13-16-26(27)28(34)30-17-8-20-33-18-6-3-7-19-33)32-29(35)31-22-11-14-25(15-12-22)37-24-9-4-2-5-10-24/h2,4-5,9-16,21H,3,6-8,17-20H2,1H3,(H,30,34)(H2,31,32,35)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using [125I]-MCH as radioligandMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
7TM Pharma A/S

Curated by ChEMBL
LigandPNGBDBM50153206(2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-pip...)
Show SMILES COc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1
Show InChI InChI=1S/C29H34N4O4/c1-36-27-21-23(13-16-26(27)28(34)30-17-8-20-33-18-6-3-7-19-33)32-29(35)31-22-11-14-25(15-12-22)37-24-9-4-2-5-10-24/h2,4-5,9-16,21H,3,6-8,17-20H2,1H3,(H,30,34)(H2,31,32,35)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using IP3 assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7TM Pharma A/S

Curated by ChEMBL
LigandPNGBDBM50153206(2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-pip...)
Show SMILES COc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1
Show InChI InChI=1S/C29H34N4O4/c1-36-27-21-23(13-16-26(27)28(34)30-17-8-20-33-18-6-3-7-19-33)32-29(35)31-22-11-14-25(15-12-22)37-24-9-4-2-5-10-24/h2,4-5,9-16,21H,3,6-8,17-20H2,1H3,(H,30,34)(H2,31,32,35)
Affinity DataIC50: 240nMAssay Description:Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assayMore data for this Ligand-Target Pair