BDBM50153206 2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-piperidin-1-yl-propyl)-benzamide::CHEMBL182554

SMILES COc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1

InChI Key InChIKey=DCMOVMXTFVOSNS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153206   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153206(2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-pip...)
Affinity DataIC50:  50nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153206(2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-pip...)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using [125I]-MCH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153206(2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-pip...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonistic activity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using IP3 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153206(2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-pip...)
Affinity DataIC50:  240nMAssay Description:Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed