BDBM50153846 4-methyl-1-[3-(1,4-oxazinan-4-yl)phenylcarboxamido]-3-[4-(1,3-thiazol-4-ylmethoxy)phenylcarboxamido]benzene::CHEMBL183630
SMILES Cc1ccc(NC(=O)c2cccc(c2)N2CCOCC2)cc1NC(=O)c1ccc(OCc2cscn2)cc1
InChI Key InChIKey=JBPMUXHYANUBMJ-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50153846
Affinity DataIC50: 10nMAssay Description:Concentration required to inhibit human mitogen activated protein kinase p38 activity More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of Smo expressed in mouse NIH/3T3 cells after 20 hrs by Gli reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of p38alpha-mediated TNFalpha secretion in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 25.1nMAssay Description:Inhibition of p38alpha-mediated TNFalpha secretion in LPS-stimulated human whole blood assessed as IC50 equals to free drug concentration at human wh...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of p38alpha-mediated TNFalpha secretion in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair