BDBM50153874 CHEMBL187007::N-[4-Chloro-3-(6,7-dimethoxy-quinazolin-4-ylamino)-phenyl]-3-dimethylamino-benzamide

SMILES COc1cc2ncnc(Nc3cc(NC(=O)c4cccc(c4)N(C)C)ccc3Cl)c2cc1OC

InChI Key InChIKey=CXXCKESOBLFJAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153874   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153874(CHEMBL187007 | N-[4-Chloro-3-(6,7-dimethoxy-quinaz...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibitory concentration against Epidermal growth factor receptor tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153874(CHEMBL187007 | N-[4-Chloro-3-(6,7-dimethoxy-quinaz...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against alpha mitogen activated protein kinase p38 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed