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BDBM50155068 CHEMBL361720::N-Ethyl-4-[(8-furan-3-ylmethyl-8-aza-bicyclo[3.2.1]oct-3-ylidene)-(4-hydroxy-3-methoxy-phenyl)-methyl]-benzamide

SMILES: [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1ccc(-[#8])c(-[#8]-[#6])c1

InChI Key: InChIKey=IZVFRMTZUWNHOR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155068   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(MOUSE)
BDBM50155068
PNG
(CHEMBL361720 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...)
Show SMILES CCNC(=O)c1ccc(cc1)C(=C1CC2CCC(C1)N2Cc1ccoc1)c1ccc(O)c(OC)c1
Show InChI InChI=1S/C29H32N2O4/c1-3-30-29(33)21-6-4-20(5-7-21)28(22-8-11-26(32)27(16-22)34-2)23-14-24-9-10-25(15-23)31(24)17-19-12-13-35-18-19/h4-8,11-13,16,18,24-25,32H,3,9-10,14-15,17H2,1-2H3,(H,30,33)
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PC cid
PC sid
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Similars

Article
PubMed
0.590n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Binding affinity against mu opioid receptor in mouse hot plate test


Bioorg Med Chem Lett 14: 5493-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.004
BindingDB Entry DOI: 10.7270/Q2X34WZV
More data for this
Ligand-Target Pair