BDBM50155426 1,3,5,8-Tetrahydroxy-xanthen-9-one::1,3,5,8-tetrahydroxy-9H-xanthen-9-one::CHEMBL184574::DEMETHYLBELLIDIFOLIN::Xanthen-9-one, 1.0

SMILES Oc1cc(O)c2c(c1)oc1c(O)ccc(O)c1c2=O

InChI Key InChIKey=MPXAWSABMVLIBU-UHFFFAOYSA-N

Data  2 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50155426   

TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50155426(1,3,5,8-Tetrahydroxy-xanthen-9-one | 1,3,5,8-tetra...)
Affinity DataKi:  140nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50155426(1,3,5,8-Tetrahydroxy-xanthen-9-one | 1,3,5,8-tetra...)
Affinity DataKi:  200nM IC50:  200nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50155426(1,3,5,8-Tetrahydroxy-xanthen-9-one | 1,3,5,8-tetra...)
Affinity DataIC50:  200nMAssay Description:Inhibition of CDK5/P25 using full length tau as substrate by colorimetric ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Unne

Curated by ChEMBL
LigandPNGBDBM50155426(1,3,5,8-Tetrahydroxy-xanthen-9-one | 1,3,5,8-tetra...)
Affinity DataIC50:  1.30E+4nMAssay Description:Concentration required to inhibit monoamine oxidase activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed