BDBM50155447 1,3,6,7-Tetrahydroxy-xanthen-9-one::1,3,6,7-tetrahydroxyxantone::CHEMBL187265

SMILES Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O

InChI Key InChIKey=ZHTQCPCDXKMMLU-UHFFFAOYSA-N

Data  1 KI  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50155447   

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-Tetrahydroxy-xanthen-9-one | 1,3,6,7-tetra...)
Affinity DataKi:  2.50E+5nMAssay Description:Inhibition of ACE by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Unne

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-Tetrahydroxy-xanthen-9-one | 1,3,6,7-tetra...)
Affinity DataIC50:  2.50E+4nMAssay Description:Concentration required to inhibit monoamine oxidase activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-Tetrahydroxy-xanthen-9-one | 1,3,6,7-tetra...)
Affinity DataIC50:  5.31E+5nMAssay Description:Inhibition of ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-Tetrahydroxy-xanthen-9-one | 1,3,6,7-tetra...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant C-terminal 6xHis-tagged MTH1 (3 to 156 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-Tetrahydroxy-xanthen-9-one | 1,3,6,7-tetra...)
Affinity DataIC50:  2.17E+4nMAssay Description:Inhibition of bovine Xanthine oxidase assessed as reduction in uric acid level by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-Tetrahydroxy-xanthen-9-one | 1,3,6,7-tetra...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of human recombinant MMP1 catalytic domain incubated for 20 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-Tetrahydroxy-xanthen-9-one | 1,3,6,7-tetra...)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed