BDBM50156056 CHEMBL188143::[4-(4-Chloro-phenyl)-piperidin-3-ylmethylsulfanyl]-acetic acid methyl ester

SMILES COC(=O)CSCC1CNCCC1c1ccc(Cl)cc1

InChI Key InChIKey=QJCSFENQSHMLKU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156056   

TargetTransporter(Rattus norvegicus)
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50156056(CHEMBL188143 | [4-(4-Chloro-phenyl)-piperidin-3-yl...)
Affinity DataKi:  0.560nMAssay Description:Inhibition of high affinity uptake by the norepinephrine transporter from rat synaptosomal nerve endings by using [3H]NE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50156056(CHEMBL188143 | [4-(4-Chloro-phenyl)-piperidin-3-yl...)
Affinity DataKi:  13nMAssay Description:Inhibition of high affinity uptake by the serotonin transporter (5-HT) from rat synaptosomal nerve endings by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50156056(CHEMBL188143 | [4-(4-Chloro-phenyl)-piperidin-3-yl...)
Affinity DataKi:  51nMAssay Description:Inhibition of high affinity uptake by the dopamine transporter from rat synaptosomal nerve endings by using [3H]DA as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed