BDBM50156343 CHEMBL3787433::US10519177, Compound P-0401

SMILES Cc1noc(C)c1-c1cnc2c(cn(CC3CCC(F)(F)CC3)c2c1)-c1ccc(N)nc1

InChI Key InChIKey=CDTZIRGMAPZYPZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156343   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50156343(CHEMBL3787433 | US10519177, Compound P-0401)
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 60 mins by Alphascreen assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM50156343(CHEMBL3787433 | US10519177, Compound P-0401)
Affinity DataIC50: <1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM50156343(CHEMBL3787433 | US10519177, Compound P-0401)
Affinity DataIC50: <1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent