BDBM501570 US11026937, Compound I-139
SMILES COc1ccc(\C=C\C(=O)c2c(-c3ccccc3)c3ccccc3[nH]c2=O)cc1
InChI Key InChIKey=YIJGNIIQDRGGFT-DTQAZKPQSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 501570
Affinity DataIC50: 1.15E+4nMAssay Description:Assay buffer (as aforementioned): 100 mM Tris-HCl (pH 7.6), 2 mM DTT, 1 mM CaCl2Final concentrations:100 nM hPAD4 enzyme50 μM (8-fold sub-Km) su...More data for this Ligand-Target Pair
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of acid ceramidase in human SK-OV-3 cell lysatesMore data for this Ligand-Target Pair
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human acid ceramidaseMore data for this Ligand-Target Pair