BDBM501570 US11026937, Compound I-139

SMILES COc1ccc(\C=C\C(=O)c2c(-c3ccccc3)c3ccccc3[nH]c2=O)cc1

InChI Key InChIKey=YIJGNIIQDRGGFT-DTQAZKPQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 501570   

TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM501570(US11026937, Compound I-139)
Affinity DataIC50:  1.15E+4nMAssay Description:Assay buffer (as aforementioned): 100 mM Tris-HCl (pH 7.6), 2 mM DTT, 1 mM CaCl2Final concentrations:100 nM hPAD4 enzyme50 μM (8-fold sub-Km) su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM501570(US11026937, Compound I-139)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of acid ceramidase in human SK-OV-3 cell lysatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM501570(US11026937, Compound I-139)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of human acid ceramidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed