BDBM50157165 (2S,3R)-3-(4-HYDROXYPHENYL)-2-(4-{[(2R)-2-PYRROLIDIN-1-YLPROPYL]OXY}PHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL::(2S,3R)-3-(4-Hydroxy-phenyl)-2-[4-((R)-2-pyrrolidin-1-yl-propoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol::CHEMBL180792

SMILES C[C@H](COc1ccc(cc1)[C@@H]1Oc2ccc(O)cc2S[C@@H]1c1ccc(O)cc1)N1CCCC1

InChI Key InChIKey=UZOOIPXOYYJULJ-BLIZRMSTSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50157165   

TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157165((2S,3R)-3-(4-HYDROXYPHENYL)-2-(4-{[(2R)-2-PYRROLID...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157165((2S,3R)-3-(4-HYDROXYPHENYL)-2-(4-{[(2R)-2-PYRROLID...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of ERalphaMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157165((2S,3R)-3-(4-HYDROXYPHENYL)-2-(4-{[(2R)-2-PYRROLID...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human estrogen receptor 2 using tritiated estradiol incubated for 3 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157165((2S,3R)-3-(4-HYDROXYPHENYL)-2-(4-{[(2R)-2-PYRROLID...)
Affinity DataIC50:  45nMAssay Description:Inhibition of binding to recombinant human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed