BDBM50157305 CHEMBL3780404

SMILES COc1ccccc1Nc1cc[nH]c(=O)c1-c1nc2c(ccc(C)c2[nH]1)C(C)C

InChI Key InChIKey=FTDKWXYBRRFDHH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157305   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50157305(CHEMBL3780404)
Affinity DataKi:  88nMAssay Description:Inhibition of human EGFR catalytic domain (668 to 1210 residues) T790M/L858R double mutant using Fl-EEPLYWSFPAKKK-CONH2 peptide substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed