BDBM50157306 CHEMBL3780509

SMILES CCc1cc(NC(=O)c2c(Nc3ccccc3OC)cc[nH]c2=O)ccc1N1CCN(C)CC1

InChI Key InChIKey=RWIQIXOKKRITPC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157306   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50157306(CHEMBL3780509)
Affinity DataKi:  31nMAssay Description:Inhibition of human EGFR catalytic domain (668 to 1210 residues) T790M/L858R double mutant using Fl-EEPLYWSFPAKKK-CONH2 peptide substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed