BDBM50157827 (2S,6R)-4-(4-Nitro-naphthalen-1-yl)-4-aza-tricyclo[5.3.2.0*2,6*]dodec-11-ene-3,5-dione::CHEMBL369542

SMILES Oc1c2C3CCCC(C=C3)c2c(O)n1-c1ccc([N+]([O-])=O)c2ccccc12

InChI Key InChIKey=VQRZUXKMLXQVAW-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157827   

TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157827((2S,6R)-4-(4-Nitro-naphthalen-1-yl)-4-aza-tricyclo...)
Affinity DataKi:  9nMAssay Description:Binding affinity for androgen receptor in human MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157827((2S,6R)-4-(4-Nitro-naphthalen-1-yl)-4-aza-tricyclo...)
Affinity DataKi:  9nMAssay Description:Binding affinity for mutant T877A Androgen receptor in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157827((2S,6R)-4-(4-Nitro-naphthalen-1-yl)-4-aza-tricyclo...)
Affinity DataIC50:  49nMAssay Description:Inhibition of androgen receptor in human MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed