BDBM50157903 CHEMBL3781988
SMILES CN1CCN(CC1)c1ccc(NC(=O)c2c(Nc3ccccn3)cc[nH]c2=O)cc1
InChI Key InChIKey=LDIRICACJZEUNH-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50157903
Affinity DataKi: 108nMAssay Description:Inhibition of human EGFR catalytic domain (668 to 1210 residues) T790M/L858R double mutant using Fl-EEPLYWSFPAKKK-CONH2 peptide substrate preincubate...More data for this Ligand-Target Pair
Affinity DataKi: >2.54E+3nMAssay Description:Inhibition of human N-terminal GST-tagged EGFR catalytic domain (669 to 1210 residues) expressed in baculovirus expression system using Fl-EEPLYWSFPA...More data for this Ligand-Target Pair