BDBM50158831 CHEMBL3785443

SMILES CC(C)Cn1cc(cn1)-c1[nH]c2c(cnn2c(=O)c1C(C)C)C#N

InChI Key InChIKey=NVCPEMIYZIDHEV-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50158831   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158831(CHEMBL3785443)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant full length FLAG-tagged KDM5A (unknown origin) expressed in sf9 cells using biotin-H3K4me3 (1 to 21 residues as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158831(CHEMBL3785443)
Affinity DataEC50:  530nMAssay Description:Inhibition of KDM5B in human PC9 cells assessed as reduction in demethylation of H3K4me3 after 120 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158831(CHEMBL3785443)
Affinity DataEC50:  530nMAssay Description:Inhibition of KDM5A in human PC9 cells assessed as reduction in demethylation of H3K4me3 after 120 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed