BDBM50159593 CHEMBL3786739

SMILES Cc1ccoc1C(=O)Nc1ccc(cc1)N1Cc2c(cccc2Cl)C1=O

InChI Key InChIKey=AUUPSFFSNGOHPV-UHFFFAOYSA-N

Data  2 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159593   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50159593(CHEMBL3786739)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1)N1Cc2c(cccc2Cl)C1=O
Show InChI InChI=1S/C20H15ClN2O3/c1-12-9-10-26-18(12)19(24)22-13-5-7-14(8-6-13)23-11-16-15(20(23)25)3-2-4-17(16)21/h2-10H,11H2,1H3,(H,22,24)
Affinity DataEC50:  245nMAssay Description:Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50159593(CHEMBL3786739)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1)N1Cc2c(cccc2Cl)C1=O
Show InChI InChI=1S/C20H15ClN2O3/c1-12-9-10-26-18(12)19(24)22-13-5-7-14(8-6-13)23-11-16-15(20(23)25)3-2-4-17(16)21/h2-10H,11H2,1H3,(H,22,24)
Affinity DataEC50:  245nMAssay Description:Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci...More data for this Ligand-Target Pair