BDBM50159688 CHEMBL3786967

SMILES Clc1cccnc1C(=O)Nc1ccc(N2Cc3ccccc3C2=O)c(Cl)c1

InChI Key InChIKey=ANLQEDUVRYARCX-UHFFFAOYSA-N

Data  2 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159688   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50159688(CHEMBL3786967)
Show SMILES Clc1cccnc1C(=O)Nc1ccc(N2Cc3ccccc3C2=O)c(Cl)c1
Show InChI InChI=1S/C20H13Cl2N3O2/c21-15-6-3-9-23-18(15)19(26)24-13-7-8-17(16(22)10-13)25-11-12-4-1-2-5-14(12)20(25)27/h1-10H,11H2,(H,24,26)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50159688(CHEMBL3786967)
Show SMILES Clc1cccnc1C(=O)Nc1ccc(N2Cc3ccccc3C2=O)c(Cl)c1
Show InChI InChI=1S/C20H13Cl2N3O2/c21-15-6-3-9-23-18(15)19(26)24-13-7-8-17(16(22)10-13)25-11-12-4-1-2-5-14(12)20(25)27/h1-10H,11H2,(H,24,26)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci...More data for this Ligand-Target Pair