BDBM50162309 5-Methyl-6-[(methyl-phenyl-amino)-methyl]-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL179319

SMILES CN(Cc1cnc2nc(N)nc(N)c2c1C)c1ccccc1

InChI Key InChIKey=SSFGEHKXRJGWSX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162309   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50162309(5-Methyl-6-[(methyl-phenyl-amino)-methyl]-pyrido[2...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50162309(5-Methyl-6-[(methyl-phenyl-amino)-methyl]-pyrido[2...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50162309(5-Methyl-6-[(methyl-phenyl-amino)-methyl]-pyrido[2...)
Affinity DataIC50:  18nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed