BDBM50164012 CHEMBL183217::Pyridine-3-sulfonic acid [6-cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-(2-methyl-allyl)-amide

SMILES CC(=C)CN(C1CN(Cc2cncn2C)c2ccc(cc2C1)C#N)S(=O)(=O)c1cccnc1

InChI Key InChIKey=NIACYCIOHPNBOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164012   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50164012(CHEMBL183217 | Pyridine-3-sulfonic acid [6-cyano-1...)
Affinity DataIC50:  100nMAssay Description:Inhibition of cellular reversion in H-ras transformed Rat-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50164012(CHEMBL183217 | Pyridine-3-sulfonic acid [6-cyano-1...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed