BindingDB logo
myBDB logout

BDBM50164713 CHEMBL370485::N*2*-(3H-Benzoimidazol-5-yl)-5-bromo-N*4*-indan-1-yl-pyrimidine-2,4-diamine

SMILES: Brc1cnc(Nc2ccc3nc[nH]c3c2)nc1NC1CCc2ccccc12

InChI Key: InChIKey=RQXGJGJDXGEQTI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164713   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-dependent kinase 1


(Homo sapiens (Human))
BDBM50164713
PNG
(CHEMBL370485 | N*2*-(3H-Benzoimidazol-5-yl)-5-brom...)
Show SMILES Brc1cnc(Nc2ccc3nc[nH]c3c2)nc1NC1CCc2ccccc12
Show InChI InChI=1S/C20H17BrN6/c21-15-10-22-20(25-13-6-8-17-18(9-13)24-11-23-17)27-19(15)26-16-7-5-12-3-1-2-4-14(12)16/h1-4,6,8-11,16H,5,7H2,(H,23,24)(H2,22,25,26,27)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 34n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against Cyclin dependent kinase 1


Bioorg Med Chem Lett 15: 1973-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.076
BindingDB Entry DOI: 10.7270/Q2610ZT5
More data for this
Ligand-Target Pair