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BDBM50165829 4'-{[4-Methyl-3-(3,3,3-trifluoro-propionylamino)-pyridin-2-ylamino]-methyl}-biphenyl-2-carboxylic acid methylamide::CHEMBL196494

SMILES: CNC(=O)c1ccccc1-c1ccc(CNc2nccc(C)c2NC(=O)CC(F)(F)F)cc1

InChI Key: InChIKey=CBZLVCMFXUKNPK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165829   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin B1 receptor


(Homo sapiens (Human))
BDBM50165829
PNG
(4'-{[4-Methyl-3-(3,3,3-trifluoro-propionylamino)-p...)
Show SMILES CNC(=O)c1ccccc1-c1ccc(CNc2nccc(C)c2NC(=O)CC(F)(F)F)cc1
Show InChI InChI=1S/C24H23F3N4O2/c1-15-11-12-29-22(21(15)31-20(32)13-24(25,26)27)30-14-16-7-9-17(10-8-16)18-5-3-4-6-19(18)23(33)28-2/h3-12H,13-14H2,1-2H3,(H,28,33)(H,29,30)(H,31,32)
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Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory constant against human Bradykinin receptor B1 expressed in chinese hamster ovary cells


Bioorg Med Chem Lett 15: 2385-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.077
BindingDB Entry DOI: 10.7270/Q2FF3RW1
More data for this
Ligand-Target Pair