BDBM50166029 CHEMBL192650::Naphthalene-2-carboxylic acid [4-((R)-10-methoxy-1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-butyl]-amide

SMILES COc1cccc2CC[C@@H]3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c12

InChI Key InChIKey=XLHPOAMYVQMRPZ-RUZDIDTESA-N

Data  3 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166029   

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50166029(CHEMBL192650 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1cccc2CC[C@@H]3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c12
Show InChI InChI=1S/C28H33N3O2/c1-33-26-10-6-9-22-13-14-25-20-30(17-18-31(25)27(22)26)16-5-4-15-29-28(32)24-12-11-21-7-2-3-8-23(21)19-24/h2-3,6-12,19,25H,4-5,13-18,20H2,1H3,(H,29,32)/t25-/m1/s1
Affinity DataKi:  4.10nMAssay Description:Inhibition of [3H]-PD 128907 binding to Dopamine receptor D3 in rat ventral striatumMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(RAT)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50166029(CHEMBL192650 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1cccc2CC[C@@H]3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c12
Show InChI InChI=1S/C28H33N3O2/c1-33-26-10-6-9-22-13-14-25-20-30(17-18-31(25)27(22)26)16-5-4-15-29-28(32)24-12-11-21-7-2-3-8-23(21)19-24/h2-3,6-12,19,25H,4-5,13-18,20H2,1H3,(H,29,32)/t25-/m1/s1
Affinity DataKi:  312nMAssay Description:Inhibition of [3H]-Spiperone binding to Dopamine receptor D2-like in rat caudate-putamen membraneMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(RAT)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50166029(CHEMBL192650 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1cccc2CC[C@@H]3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c12
Show InChI InChI=1S/C28H33N3O2/c1-33-26-10-6-9-22-13-14-25-20-30(17-18-31(25)27(22)26)16-5-4-15-29-28(32)24-12-11-21-7-2-3-8-23(21)19-24/h2-3,6-12,19,25H,4-5,13-18,20H2,1H3,(H,29,32)/t25-/m1/s1
Affinity DataKi:  7.59E+3nMAssay Description:Inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1-like in rat brainMore data for this Ligand-Target Pair