BDBM50166031 CHEMBL427173::Naphthalene-2-carboxylic acid [(S)-4-(1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-butyl]-amide

SMILES O=C(NCCCCN1CCN2[C@@H](CCc3ccccc23)C1)c1ccc2ccccc2c1

InChI Key InChIKey=KIVKVDKAEVGINM-VWLOTQADSA-N

Data  3 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166031   

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50166031(CHEMBL427173 | Naphthalene-2-carboxylic acid [(S)-...)
Show SMILES O=C(NCCCCN1CCN2[C@@H](CCc3ccccc23)C1)c1ccc2ccccc2c1
Show InChI InChI=1S/C27H31N3O/c31-27(24-12-11-21-7-1-2-9-23(21)19-24)28-15-5-6-16-29-17-18-30-25(20-29)14-13-22-8-3-4-10-26(22)30/h1-4,7-12,19,25H,5-6,13-18,20H2,(H,28,31)/t25-/m0/s1
Affinity DataKi:  16nMAssay Description:Inhibition of [3H]-PD 128907 binding to Dopamine receptor D3 in rat ventral striatumMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(RAT)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50166031(CHEMBL427173 | Naphthalene-2-carboxylic acid [(S)-...)
Show SMILES O=C(NCCCCN1CCN2[C@@H](CCc3ccccc23)C1)c1ccc2ccccc2c1
Show InChI InChI=1S/C27H31N3O/c31-27(24-12-11-21-7-1-2-9-23(21)19-24)28-15-5-6-16-29-17-18-30-25(20-29)14-13-22-8-3-4-10-26(22)30/h1-4,7-12,19,25H,5-6,13-18,20H2,(H,28,31)/t25-/m0/s1
Affinity DataKi:  180nMAssay Description:Inhibition of [3H]-Spiperone binding to Dopamine receptor D2-like in rat caudate-putamen membraneMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(RAT)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50166031(CHEMBL427173 | Naphthalene-2-carboxylic acid [(S)-...)
Show SMILES O=C(NCCCCN1CCN2[C@@H](CCc3ccccc23)C1)c1ccc2ccccc2c1
Show InChI InChI=1S/C27H31N3O/c31-27(24-12-11-21-7-1-2-9-23(21)19-24)28-15-5-6-16-29-17-18-30-25(20-29)14-13-22-8-3-4-10-26(22)30/h1-4,7-12,19,25H,5-6,13-18,20H2,(H,28,31)/t25-/m0/s1
Affinity DataKi:  258nMAssay Description:Inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1-like in rat brainMore data for this Ligand-Target Pair