BDBM50166748 CHEMBL3799426

SMILES COc1cc(CCc2cc(Nc3ncnc4cc(ccc34)N3CCN(CC3)C3CCC3)n[nH]2)cc(OC)c1

InChI Key InChIKey=WXNBLYTUMAZZAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166748   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166748(CHEMBL3799426)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of recombinant FGFR2 in human SNU16 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166748(CHEMBL3799426)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed