BDBM50167290 (1S)-2-cyclohexyl-1-methylethyl 2-cyano-2-isopropylhydrazinecarboxylate::CHEMBL371420

SMILES C[C@@H](CC1CCCCC1)OC(=O)NN(C#N)C(C)C

InChI Key InChIKey=YCYQOGPWUSMXGX-LBPRGKRZSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50167290   

TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50167290((1S)-2-cyclohexyl-1-methylethyl 2-cyano-2-isopropy...)
Affinity DataKi:  0.0190nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-cathepsin H(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50167290((1S)-2-cyclohexyl-1-methylethyl 2-cyano-2-isopropy...)
Affinity DataKi:  0.460nMAssay Description:Inhibition constant against human cathepsin H using L-Arg-b-naphthalamideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50167290((1S)-2-cyclohexyl-1-methylethyl 2-cyano-2-isopropy...)
Affinity DataKi:  0.790nMAssay Description:Inhibition constant against human cathepsin L using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50167290((1S)-2-cyclohexyl-1-methylethyl 2-cyano-2-isopropy...)
Affinity DataKi:  1.30nMAssay Description:Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed