BDBM50167609 (2R,5R)-1-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-5-hydroxy-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL179552
SMILES CC1(C)C[C@@H](O)CN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccc(Cl)cc2Cl)cc1
InChI Key InChIKey=GBGAKFWYCGVPHY-BEFAXECRSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50167609
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant aggrecanase 1 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 (MMP-13)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-1 (MMP-1)More data for this Ligand-Target Pair