BDBM50167929 CHEMBL3798702

SMILES Cc1nc(ccc1-c1cc(cc2[nH]ncc12)C(F)(F)F)N1CC[C@@H](O)C1

InChI Key InChIKey=PWRMQUDNGXLDFA-GFCCVEGCSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167929   

TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50167929(CHEMBL3798702)
Affinity DataEC50:  38nMAssay Description:Inhibition of MetAP2 in HUVEC assessed as accumulation of N-Met-14-3-3gamma after 24 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50167929(CHEMBL3798702)
Affinity DataIC50:  5nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed