BDBM50168042 3-(4-Fluoro-3-methyl-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL195738

SMILES COC(=O)C1C2CCC(CC1c1ccc(F)c(C)c1)N2

InChI Key InChIKey=MMLRFWSQUZRITP-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50168042   

TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50168042(3-(4-Fluoro-3-methyl-phenyl)-8-aza-bicyclo[3.2.1]o...)
Affinity DataKi:  2.12nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50168042(3-(4-Fluoro-3-methyl-phenyl)-8-aza-bicyclo[3.2.1]o...)
Affinity DataKi:  17.1nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50168042(3-(4-Fluoro-3-methyl-phenyl)-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50:  4.23nMAssay Description:Inhibition of [3H]nisoxetine binding to rat cerebral cortex norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50168042(3-(4-Fluoro-3-methyl-phenyl)-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50:  9.38nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50168042(3-(4-Fluoro-3-methyl-phenyl)-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50:  69.8nMAssay Description:Inhibition of [3H]paroxetine binding to rat cortex serotonin transporter More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed