BDBM50168964 (3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamino]-decahydro-isoquinoline-3-carboxylic acid::CHEMBL191249

SMILES OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Nc1ccccc1-c1nnn[nH]1

InChI Key InChIKey=SPIBJDVGRFDGQS-OXIQGZBJSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50168964   

TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Centro De Investigaci�N Lilly

Curated by ChEMBL
LigandPNGBDBM50168964((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]ATPA from human Gluk1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Centro De Investigaci�N Lilly

Curated by ChEMBL
LigandPNGBDBM50168964((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...)
Affinity DataKi:  1.55E+3nMAssay Description:Inhibition of [3H]-KA binding to iontropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50168964((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...)
Affinity DataKi:  5.51E+3nMAssay Description:Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50168964((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50168964((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of [3H]-KA binding to iontropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed