BDBM50168995 (-)-swainsonine::(1S,2R,8R,8aR)-Octahydro-indolizine-1,2,8-triol::1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL::CHEMBL371197::SWAINSONINE
SMILES O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O
InChI Key InChIKey=FXUAIOOAOAVCGD-WCTZXXKLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50168995
Affinity DataKi: 3nM ΔG°: -11.6kcal/mole IC50: 37nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
TargetMannosyl-oligosaccharide alpha-1,2-mannosidase IA(Drosophila melanogaster)
Slovak Academy Of Sciences
Curated by ChEMBL
Slovak Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of Drosophila melanogaster GM2b by spectrophotometryMore data for this Ligand-Target Pair
TargetAlpha-1,2-mannosidase, putative(Bacteroides thetaiotaomicron )
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3990 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
TargetAlpha-1,2-mannosidase, putative(Bacteroides thetaiotaomicron )
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2199 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
TargetMannosyl-oligosaccharide alpha-1,2-mannosidase IA(Drosophila melanogaster)
Slovak Academy Of Sciences
Curated by ChEMBL
Slovak Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of Drosophila melanogaster GM2b by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: >1.15E+6nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering
Curated by ChEMBL
Institute Of Chemical Sciences And Engineering
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Concentration of compound inhibiting alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair