BDBM501705 4-(2-(Dimethylamino)ethoxy)-6-((6-methoxypyridin-3-yl)methyl)-2-methyl-9H-xanthen-9-one::US11028064, Example 19

SMILES COc1cc(C)cc2c1oc1cc(ccc1c2=O)B1OC(C)(C)C(C)(C)O1

InChI Key InChIKey=DHFJIRXNTBLHPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501705   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501705(4-(2-(Dimethylamino)ethoxy)-6-((6-methoxypyridin-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501705(4-(2-(Dimethylamino)ethoxy)-6-((6-methoxypyridin-3...)
Affinity DataIC50:  550nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent