BDBM50172350 CHEMBL3810142

SMILES Clc1ccc2ccc(\C=C\c3cccc(COC(=O)\C=C\c4c[nH]c5cc(Cl)cc(Cl)c45)c3)nc2c1

InChI Key InChIKey=HFXNFYJSMCRIAG-BFFNUNQPSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172350   

TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50172350(CHEMBL3810142)
Show SMILES Clc1ccc2ccc(\C=C\c3cccc(COC(=O)\C=C\c4c[nH]c5cc(Cl)cc(Cl)c45)c3)nc2c1
Show InChI InChI=1S/C29H19Cl3N2O2/c30-22-8-5-20-6-10-24(34-26(20)14-22)9-4-18-2-1-3-19(12-18)17-36-28(35)11-7-21-16-33-27-15-23(31)13-25(32)29(21)27/h1-16,33H,17H2/b9-4+,11-7+
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity against CysLT2 receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of LTD4-induced calcium mobilization pr...More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50172350(CHEMBL3810142)
Show SMILES Clc1ccc2ccc(\C=C\c3cccc(COC(=O)\C=C\c4c[nH]c5cc(Cl)cc(Cl)c45)c3)nc2c1
Show InChI InChI=1S/C29H19Cl3N2O2/c30-22-8-5-20-6-10-24(34-26(20)14-22)9-4-18-2-1-3-19(12-18)17-36-28(35)11-7-21-16-33-27-15-23(31)13-25(32)29(21)27/h1-16,33H,17H2/b9-4+,11-7+
Affinity DataIC50: 3.10E+4nMAssay Description:Antagonist activity against CysLT1 receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of LTD4-induced calcium mobilization pr...More data for this Ligand-Target Pair