BDBM50172366 CHEMBL3809739

SMILES CSCCC(NC(=O)C(CS)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCNC(N)=N)NC(=O)C1CCC(=O)N1)C(=O)N1CCCC1C(=O)NC(CC(C)C)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CO)C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)C)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)N1CCCC1C(O)=O

InChI Key InChIKey=LKYSPGTYQNANFL-SVHQDZQYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50172366   

TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50172366(CHEMBL3809739)
Affinity DataKi:  0.930nMAssay Description:Displacement of [125I]-Apelin-13[Glp65, Nle75, Tyr77] from YFP epitope-tagged human APJ expressed in HEK-293 cells after 1 hr by gamma counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50172366(CHEMBL3809739)
Affinity DataEC50:  36nMAssay Description:Induction of HA-tagged human APJ receptor internalization expressed in HEK-293 cells after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50172366(CHEMBL3809739)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at human APJ receptor expressed in HEK-293 cells assessed as dissociation of G-alpha-i1 protein after 5 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50172366(CHEMBL3809739)
Affinity DataEC50:  166nMAssay Description:Agonist activity at human APJ receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment after 30 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed