BDBM50172865 4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide::4-fluoro-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzamide::CHEMBL194727

SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(F)cc2)CC1

InChI Key InChIKey=HGRPPZKIXIZLRX-UHFFFAOYSA-N

Data  6 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50172865   

TargetD(3) dopamine receptor(Homo sapiens (Human))
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50172865(4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C22H28FN3O2/c1-28-21-7-3-2-6-20(21)26-16-14-25(15-17-26)13-5-4-12-24-22(27)18-8-10-19(23)11-9-18/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,27)
Affinity DataKi:  4.30nMAssay Description:Binding affinity towards Dopamine receptor D3 using CHO cell line and [3H]-spiperone as radioligand More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50172865(4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C22H28FN3O2/c1-28-21-7-3-2-6-20(21)26-16-14-25(15-17-26)13-5-4-12-24-22(27)18-8-10-19(23)11-9-18/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,27)
Affinity DataKi:  15nMAssay Description:Binding affinity towards 5-HT1A receptor using porcine cortical membraneand [3H]-8-OH-DPAT as radioligand More data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50172865(4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C22H28FN3O2/c1-28-21-7-3-2-6-20(21)26-16-14-25(15-17-26)13-5-4-12-24-22(27)18-8-10-19(23)11-9-18/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,27)
Affinity DataKi:  34nMAssay Description:Binding affinity towards Dopamine receptor D 4.4 using CHO cell line and [3H]-spiperone as radioligand More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50172865(4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C22H28FN3O2/c1-28-21-7-3-2-6-20(21)26-16-14-25(15-17-26)13-5-4-12-24-22(27)18-8-10-19(23)11-9-18/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,27)
Affinity DataKi:  98nMAssay Description:Binding affinity towards Dopamine D2L receptor using CHO cell line and [3H]-spiperone as radioligand More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50172865(4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C22H28FN3O2/c1-28-21-7-3-2-6-20(21)26-16-14-25(15-17-26)13-5-4-12-24-22(27)18-8-10-19(23)11-9-18/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,27)
Affinity DataKi:  140nMAssay Description:Binding affinity towards Dopamine D2S receptor using CHO cell line and [3H]-spiperone as radioligand More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Sus scrofa)
University of Erlangen-Nuremberg

Curated by ChEMBL
LigandPNGBDBM50172865(4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C22H28FN3O2/c1-28-21-7-3-2-6-20(21)26-16-14-25(15-17-26)13-5-4-12-24-22(27)18-8-10-19(23)11-9-18/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,27)
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity towards Dopamine receptor D1 using porcine striatal membrane and [3H]-SCH- 23390 as radioligand More data for this Ligand-Target Pair